I'm running a 3.73 open diff with stock wheels right now. It's a very common E30 ratio, most of the M20B25 cars used it. It is a great mod for highway use, but it does take a little off the car's acceleration. If you're also running larger circumference tires it'd even be worse. I don't mind, and I typically start in 2nd gear to save synchro & thrust bearing wear.
I'd assume the taller diff probably saves a bit of gas too. I don't have a 4.10 baseline (that diff was broken when I bought the car). My fuel logs reported an average of 29MPG at 60% highway before I did any other fuel saving mods.
I just got lucky, the Z3 donor I found (locally

) had a 3.46. That's slightly low for a stock E30 M42...but ideal for an E24 with a "dirty" Euro M30 turning a Getrag 265.

IIRC the donor was a relatively rare M54B22 5-speed ('02 Z3 2.3i?).