Update:
Ended up replacing my central lock relay 3 times and all my door locks 1 time.
After numerous troubleshooting, I found a small crack in the rubber booting connecting the door to the chassis where the wires run through. Under heavy rains, the water would seep into it and travel down to the lower kickpanel where your speaker and central door lock relay is and cause it to get wet, including the wiring.
This eventually shorted out my central door lock relay and on the 3rd replacement, also shorted out all my door locks.
I've since siliconed the rubber boot and relocated my central door lock relay from the kick panel(poor placement anyway) to under the dash.
Cliff Notes: Check your rubber boot that goes from the door to the chassis for any leaks which can damage your central lock relay/door actuators.