You do realize that an MM 2.1 with a DA supercharger is, at a bare minimum, a $10,000 affair right?
I'm reasonably certain I could make 300hp with half the money and that includes rebuilding the engine.
The other problem is that the DA supercharger isn't capable of 300hp. You can bolt it to a 3L... it's still only going to move a certain amount of air.
Probably will be around $10k, but what is being proposed is not going to be cheap in the end either. Any idea how hard tuning a dual supercharged engine will be? Ask Audi.
You may make it for $5k. I (really) doubt it, but just maybe. If you know the right people to help, know a ton yourself, and have lots of friends who can score you some really good deals. One small problem or 2 and you are going to easily going to be at the same price.
Think about it, most rebuilds are a few grand, yes, you can do it yourself. However, a lot needs to be done by a pro with a machine shop. Parts for a rebuild are not all that cheap. Plus tools to do it properly.
Then there is the blower. Got a killer deal on that? Roots, yes, you can go cheap. Get a bad one though and lot of money has already been wasted.
Turbo, may as well rebuild that too before you start.
Put it all together, then start in on fueling and ignition. Megasquirt is the cheapest. In the end, expect AT LEAST a grand. Need somone to tune it, expect good money.
Various systems, something that will be lots of fun. Making both systems work will be a nightmare, unless you wimp out and go one into the other, which is honestly, not a good thing to do. Regardless you still need intercooling, larger radiator, exhaust, injectors, fuel plumbing and such. Then there is tuning itself, getting agood fuel map on this will be an utter nightmare, even for a professional. If your intake system is funky, expect even more costs.
Any small mistake, could self destruct the entire system.
Then you start from scratch.
As for the D.A. supercharger, yes it is capable of 300hp. Especially you do a pulley swap. That supercharger has been shown to be capable of 280hp and more. Look into Mini superchargers.
Think about this, how much is all of this going to add to your front end? Turbo system, blower, intercooler, etc... Not to mention heat.
Speed costs money, how fast can you afford to go?
A much easier and cheaper method than all of this is either start with either an M10 or M20 engine. Or better yet, an SBC. In the end, the weight will be the same, or less, and be FAR cheaper than trying to go dual supercharged on an M42.